Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.31 |
| ▸ | APAF1 | O14727 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9680321 | 0.98 | NPSR1 (0.36) | NPSR1RXFP1MAPTKDM4EAPAF1 | |
| SCHEMBL9681383 | 0.86 | NPC1 (0.34) | NPSR1RXFP1MAPTKDM4EAPAF1 | |
| SCHEMBL9846089 | 0.85 | NPSR1 (0.38) | NPSR1RXFP1MAPTKDM4EAPAF1 | |
| SCHEMBL9682084 | 0.84 | MAPT (0.36) | NPSR1RXFP1MAPTKDM4EAPAF1 | |
| SCHEMBL9680861 | 0.83 | SLC2A1 (0.38) | MAPTKDM4EAPAF1RECQLGAA | |
| SCHEMBL9681299 | 0.81 | MAPT (0.35) | MAPTKDM4EAPAF1RECQLNPC1 | |
| SCHEMBL9681421 | 0.81 | MAPT (0.37) | MAPTKDM4EAPAF1RECQLNPC1 | |
| SCHEMBL9846123 | 0.80 | NPSR1 (0.36) | NPSR1RXFP1MAPTKDM4EAPAF1 | |
| SCHEMBL9681349 | 0.78 | MAPT (0.40) | MAPTKDM4EAPAF1RECQLNPC1 | |
| SCHEMBL9682064 | 0.71 | MAPT (0.34) | MAPTKDM4EAPAF1RECQLGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | claimed |
| EP-0481802-A1 | Hydroxylated inhibitors of HIV reverse transcriptase | MERCK & CO. INC. (US) | 1992-04-22 | — | — | EP | disclosed |