SCHEMBL9681566

SCHEMBL9681566

CCCCCCCCCCCCCC(=O)NCP(=O)(O)O

nearest known ligand 0.62

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
FAAH O00519 6/20 0.62
LPAR1 Q92633 4/20 0.56
HSP90AA1 P07900 1/20 0.53
DNM1 Q05193 2/20 0.51
LPAR2 Q9HBW0 3/20 0.51
ENPP2 Q13822 2/20 0.50
CASP2 P42575 1/20 0.50
DGAT2 Q96PD7 1/20 0.49
MEN1 O00255 1/20 0.48
MAPK1 P28482 1/20 0.48
KMT2A Q03164 1/20 0.48
EPHX2 P34913 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10819092 0.84 CASP2 (0.47) FAAHLPAR1CASP2
Lithium Ion SCHEMBL7946967 0.81 FAAH (0.58) FAAHLPAR1HSP90AA1DNM1CASP2
SCHEMBL9219896 0.81 LPAR1 (0.70) FAAHLPAR1DNM1LPAR2ENPP2
SCHEMBL8456831 0.81 LPAR1 (0.70) FAAHLPAR1DNM1LPAR2ENPP2
Phosphoric Acid SCHEMBL27564924 0.81 FAAH (0.68) FAAHLPAR1DNM1LPAR2ENPP2
SCHEMBL28254595 0.78 FAAH (0.69) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL25008200 0.77 FAAH (0.77) FAAHHSP90AA1DNM1CASP2EPHX2
N-Ethylpalmitamide SCHEMBL4148137 0.77 FAAH (1.00) FAAHHSP90AA1DNM1CASP2MEN1
SCHEMBL8461970 0.77 FAAH (0.77) FAAHHSP90AA1DNM1CASP2EPHX2
SCHEMBL135555 0.77 FAAH (0.77) FAAHHSP90AA1DNM1CASP2EPHX2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0499521-A1 Inhibitors of N-myristoyltransferase, their preparation process and pharmaceutical compositions containing them ADIR ET COMPAGNIE (FR) 1992-08-19 EP disclosed