Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ENPP2 | Q13822 | 1/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
| ▸ | CDK1 | P06493 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | NPC1 | O15118 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.43 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA12 | O43570 | 1/20 | 0.42 |
| ▸ | CA9 | Q16790 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ATAD2 | Q6PL18 | 1/20 | 0.42 |
| ▸ | CECR2 | Q9BXF3 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6432425 | 0.88 | ENPP2 (0.74) | ENPP2ALDH1A1CDK1KDM4EMEN1 | |
| SCHEMBL9321055 | 0.79 | ENPP2 (0.91) | ENPP2ALDH1A1CDK1KDM4EMEN1 | |
| SCHEMBL14358432 | 0.79 | ENPP2 (0.91) | ENPP2ALDH1A1CDK1KDM4EMEN1 | |
| SCHEMBL9459333 | 0.79 | ENPP2 (0.55) | ENPP2ALDH1A1CDK1KDM4EMEN1 | |
| SCHEMBL14502114 | 0.79 | ALDH1A1 (0.76) | ENPP2ALDH1A1CDK1MEN1NPC1 | |
| SCHEMBL16272370 | 0.79 | ENPP2 (0.57) | ENPP2ALDH1A1CDK1KDM4EMEN1 | |
| SCHEMBL7055271 | 0.79 | MEN1 (0.50) | ENPP2ALDH1A1KDM4EMEN1NPC1 | |
| SCHEMBL29047638 | 0.78 | POLB (0.56) | ENPP2ALDH1A1CDK1KDM4EMEN1 | |
| Hydrochloric Acid SCHEMBL7531560 | 0.78 | ALDH1A1 (0.73) | ENPP2ALDH1A1CDK1MEN1NPC1 | |
| SCHEMBL1755227 | 0.78 | ENPP2 (0.56) | ENPP2ALDH1A1CDK1MEN1NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128455-A | WATER-SOLUBLE FIBER-REACTIVE DYES, CONTAINING AN AMINO-SUBSTITUTED 5-TRIAZINE RING WITH A FIBER-REACTIVE GROUP OF THE VINYLSULFONE SERIES | HOECHST AKTIENGESELLSCHAFT (DE) | 1992-07-07 | — | — | US | disclosed |
| EP-0374911-A1 | Water-soluble, fibre-reactive dyes, methods for their preparation and their use | HOECHST AKTIENGESELLSCHAFT (DE) | 1990-06-27 | — | — | EP | disclosed |
| US-4912244-A | Vinylsulfonylalkylamino-alkylamines as intermediates for the preparation of fiber-reactive dyes | CIBA-GEIGY CORPORATION (US) | 1990-03-27 | — | — | US | disclosed |
| US-4782140-A | Triazinyl reactive dyes containing additional fiber reactive groups bound through the sulfonylalkylaminoalkylamino bridge | CIBA-GIEGY CORPORATION (US) | 1988-11-01 | — | — | US | disclosed |
| EP-0144766-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-10-05 | — | — | EP | disclosed |
| US-4754023-A | Reactive dyestuffs comprising a triazine moiety and a vinylsulfonyl moiety both being linked by a substituted alkylene bridge member | CIBA-GEIGY CORPORATION (US) | 1988-06-28 | — | — | US | disclosed |
| EP-0159292-B1 | REACTIVE DYES, THEIR PREPARATION AND THEIR USE | CIBA-GEIGY AG (CH) | 1988-01-07 | — | — | EP | disclosed |
| EP-0159292-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-10-23 | — | — | EP | disclosed |
| EP-0144766-A2 | Reactive dyes, their preparation and their use | CIBA-GEIGY AG (CH) | 1985-06-19 | — | — | EP | disclosed |