Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.71 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.71 |
| ▸ | TSHR | P16473 | 1/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.71 |
| ▸ | HPGD | P15428 | 4/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.54 |
| ▸ | MAPT | P10636 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | PLK1 | P53350 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | SLC18A3 | Q16572 | 1/20 | 0.40 |
| ▸ | POLB | P06746 | 3/20 | 0.38 |
| ▸ | F10 | P00742 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20204952 | 0.94 | ALDH1A1 (0.79) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL9679674 | 0.87 | ALDH1A1 (0.75) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL725932 | 0.86 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL725901 | 0.86 | ALDH1A1 (0.73) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL9680410 | 0.84 | SMN1; SMN2 (0.51) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL10941271 | 0.83 | SMN1; SMN2 (0.49) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL2704635 | 0.83 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL10890719 | 0.83 | ALDH1A1 (0.69) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL27554 | 0.83 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD | |
| SCHEMBL14246539 | 0.83 | ALDH1A1 (1.00) | ALDH1A1SMN1; SMN2TSHRMAPK1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4582862-A | QUICK-SETTING PRINTING INKS BASED ON ACRYLATED RESINS | CIBA-GEIGY CORPORATION (US) | 1986-04-15 | — | — | US | disclosed |