SCHEMBL725932

SCHEMBL725932

CSc1ccc(C(=O)C(C)(C)N2CCCCC2)cc1

nearest known ligand 0.73

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.73
TSHR P16473 4/20 0.73
MAPK1 P28482 1/20 0.73
SMN1; SMN2 Q16637 1/20 0.73
MEN1 O00255 1/20 0.53
KMT2A Q03164 1/20 0.53
TNF P01375 1/20 0.45
PLK1 P53350 1/20 0.42
POLB P06746 1/20 0.41
RXFP1 Q9HBX9 1/20 0.41
HPGD P15428 5/20 0.41
HSD17B10 Q99714 2/20 0.41
KDM4E B2RXH2 1/20 0.40
LMNA P02545 1/20 0.40
EPHX2 P34913 1/20 0.38
NR1H4 Q96RI1 1/20 0.38
MLYCD O95822 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2C9 P11712 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL725901 1.00 ALDH1A1 (0.73) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL9679674 0.98 ALDH1A1 (0.75) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL20204952 0.92 ALDH1A1 (0.79) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL9681607 0.86 ALDH1A1 (0.71) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL11896654 0.86 ALDH1A1 (0.63) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL14246539 0.84 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL27554 0.84 ALDH1A1 (1.00) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL2704635 0.84 ALDH1A1 (0.69) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL10890719 0.84 ALDH1A1 (0.69) ALDH1A1TSHRMAPK1SMN1; SMN2MEN1
SCHEMBL9680468 0.83 ALDH1A1 (0.52) ALDH1A1TSHRMAPK1SMN1; SMN2HPGD

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5667541-A BINDER FROM FREE RADICAL POLYMERIZED ACRYLATED RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US claimed
EP-4273237-A1 TRANSAMINASE MUTANT AND APPLICATION THEREOF Asymchem Laboratories (Tianjin) Co., Ltd. (CN) 2023-11-08 EP disclosed
US-20230231142-A1 FUNCTIONALIZED CROSS-LINKED POLYMER NETWORKS, METHODS OF MAKING SAME, AND USES THEREOF CORNELL UNIVERSITY 2023-07-20 US disclosed
US-10005928-B2 Adhesive composition and display device SAMSUNG DISPLAY CO., LTD. (KR) 2018-06-26 US disclosed
US-20170275427-A1 PROCESS FOR PRODUCING A COMPOSITE ARTICLE DOW GLOBAL TECHNOLOGIES LLC (US) 2017-09-28 US disclosed
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
EP-2585431-B1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2017-09-06 EP disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
US-9657435-B2 Metal free bleaching composition BASF SE (DE) 2017-05-23 US disclosed
WO-2012000846-A1 METAL FREE BLEACHING COMPOSITION BASF SE (DE) 2012-01-05 WO disclosed
US-20110218266-A1 PHOTOINITIATOR MIXTURES BASF SE (DE) 2011-09-08 US disclosed
US-20100236707-A1 METHOD OF BONDING CIBA CORPORATION 2010-09-23 US disclosed
US-20080081124-A1 INK JET INK COMPOSITION, AND IMAGE FORMATION METHOD AND RECORDED MATERIAL EMPLOYING SAME FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
US-20080081124-A1 INK JET INK COMPOSITION, AND IMAGE FORMATION METHOD AND RECORDED MATERIAL EMPLOYING SAME FUJIFILM CORPORATION (JP) 2008-04-03 US disclosed
EP-0654323-B1 Coatable composition and methods of making abrasive articles MINNESOTA MINING & MFG (US) 2005-04-20 EP disclosed
US-5667541-A BINDER FROM FREE RADICAL POLYMERIZED ACRYLATED RESINS MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1997-09-16 US disclosed
EP-0654323-A1 Coatable compositions, abrasive articles made therefrom, and methods of making and using same MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1995-05-24 EP disclosed
US-5145885-A Morpholine compound, binders CIBA-GEIGY CORPORATION (US) 1992-09-08 US disclosed
US-4992547-A Aminoaryl ketone photoinitiators CIBA-GEIGY CORPORATION (US) 1991-02-12 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20100236707-A1 METHOD OF BONDING CDH1, RAD51, COL1A1 ALDH1A1 196/4885TSHR 4650/4885MAPK1 3817/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.