Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | NOTUM | Q6P988 | 2/20 | 0.51 |
| ▸ | MGAM | O43451 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SI | P14410 | 1/20 | 0.51 |
| ▸ | MGAM2 | Q2M2H8 | 1/20 | 0.51 |
| ▸ | KDM1A | O60341 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PTGS2 | P35354 | 3/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 3/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17481700 | 0.84 | ALDH1A1 (0.53) | KDM4EGAAKDM1AMEN1LMNA | |
| SCHEMBL4419209 | 0.84 | MGAM (0.53) | KDM4ENOTUMMGAMGAASI | |
| SCHEMBL7905128 | 0.82 | CA1 (0.51) | KDM4EMEN1LMNAALOX12HTT | |
| SCHEMBL9359824 | 0.76 | ALDH1A1 (0.50) | KDM4EGAAMEN1LMNAHTT | |
| SCHEMBL9870456 | 0.76 | RECQL (0.41) | KDM4EMEN1LMNAHTTKMT2A | |
| SCHEMBL29291084 | 0.76 | ALDH1A1 (0.55) | MEN1LMNAHTTKMT2ACA12 | |
| SCHEMBL9871586 | 0.73 | POLB (0.40) | MEN1KMT2ACA12CA1CA2 | |
| SCHEMBL3246946 | 0.73 | PTGS2 (0.43) | KDM4EGAAPTGS2CA12CA1 | |
| SCHEMBL8707903 | 0.73 | KDM4E (0.67) | KDM4ENOTUMMGAMGAASI | |
| SCHEMBL9508988 | 0.73 | CA1 (0.47) | KDM4ERAB9ACA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0486798-A1 | Fungicidal agents based on heterocyclic substituted sulphones | BAYER AG (DE) | 1992-05-27 | — | — | EP | claimed |