Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 4/20 | 0.47 |
| ▸ | PDE4B | Q07343 | 4/20 | 0.47 |
| ▸ | PDE4C | Q08493 | 4/20 | 0.47 |
| ▸ | PDE4D | Q08499 | 4/20 | 0.47 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA4 | P22748 | 1/20 | 0.43 |
| ▸ | CA6 | P23280 | 1/20 | 0.43 |
| ▸ | CA7 | P43166 | 1/20 | 0.43 |
| ▸ | TPMT | P51580 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10886045 | 0.72 | RAB9A (0.34) | RAB9AGAA | |
| SCHEMBL5334825 | 0.72 | ALDH1A1 (0.40) | ALDH1A1TSHRMAPTGAAL3MBTL1 | |
| SCHEMBL10458872 | 0.70 | KMT2A (0.46) | PDE4APDE4BPDE4CPDE4DMCL1 | |
| SCHEMBL335681 | 0.66 | MAPK1 (0.77) | ALDH1A1HTTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29415167 | 0.66 | MAPK1 (0.77) | ALDH1A1HTTCYP1A2CYP3A4CYP2C9 | |
| Hydrochloric Acid SCHEMBL5154533 | 0.65 | MAPK1 (0.74) | ALDH1A1HTTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL1493250 | 0.64 | CYP1A2 (1.00) | ALDH1A1HTTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL29618985 | 0.64 | TSHR (0.76) | ALDH1A1CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL3758910 | 0.64 | TSHR (0.76) | ALDH1A1CYP1A2CYP3A4CYP2C9TSHR | |
| SCHEMBL4826226 | 0.64 | CYP1A2 (0.75) | ALDH1A1HTTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5145885-A | Morpholine compound, binders | CIBA-GEIGY CORPORATION (US) | 1992-09-08 | — | — | US | disclosed |
| US-4992547-A | Aminoaryl ketone photoinitiators | CIBA-GEIGY CORPORATION (US) | 1991-02-12 | — | — | US | disclosed |
| US-4900823-A | PHOTOINITIATORS FOR PHOTOCURING | CIBA-GEIGY CORPORATION (US) | 1990-02-13 | — | — | US | disclosed |
| US-4739052-A | PHOTOINITIATORS | CIBA-GEIGY CORPORATION (US) | 1988-04-19 | — | — | US | disclosed |
| US-4559371-A | FOR PRINTING INKS AND PAINTS | CIBA GEIGY CORPORATION (US) | 1985-12-17 | — | — | US | disclosed |
| EP-0117233-A1 | Coloured photo-curable mouldings | CIBA-GEIGY AG (CH) | 1984-08-29 | — | — | EP | disclosed |