Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 1/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | NPC1 | O15118 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | CASP3 | P42574 | 1/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.40 |
| ▸ | HBB | P68871 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.40 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.40 |
| ▸ | PDE4A | P27815 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.38 |
| ▸ | PDE4C | Q08493 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | PDE3B | Q13370 | 1/20 | 0.38 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10935618 | 0.84 | POLB (0.67) | POLBALDH1A1CYP3A4TSHRNPC1 | |
| SCHEMBL9681683 | 0.79 | ALDH1A1 (0.45) | POLBALDH1A1CYP3A4TSHRNPC1 | |
| SCHEMBL2849079 | 0.78 | ESR2 (0.42) | POLBALDH1A1CYP3A4TSHRRAB9A | |
| SCHEMBL2852708 | 0.78 | PDE4A (0.44) | POLBALDH1A1CYP3A4TSHRRAB9A | |
| SCHEMBL28754177 | 0.78 | PDE4A (0.44) | POLBALDH1A1CYP3A4TSHRESR2 | |
| Hydrochloric Acid SCHEMBL28477097 | 0.77 | PDE4A (0.43) | POLBALDH1A1CYP3A4TSHRESR2 | |
| SCHEMBL28278761 | 0.74 | ESR2 (0.42) | POLBALDH1A1RAB9AESR2PDE4A | |
| SCHEMBL3974332 | 0.74 | AKT2 (0.48) | POLBALDH1A1CYP3A4TSHRNPC1 | |
| SCHEMBL27685032 | 0.74 | NPC1 (0.52) | POLBALDH1A1CYP3A4TSHRNPC1 | |
| SCHEMBL2458337 | 0.74 | POLB (0.50) | POLBALDH1A1CYP3A4TSHRNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114014961-A | Large steric hindrance ortho-benzene bridge bimetal alpha-diimine catalyst, preparation method and application | 大连理工大学 | 2022-02-08 | — | — | CN | disclosed |
| US-5112942-A | Copolymers, aromatic diamine with alkyl substituents and phenoxy substituted aromatic diamine, resistance to stess cracking | ETHYL CORPORATION (US) | 1992-05-12 | — | — | US | disclosed |