SCHEMBL9681824

SCHEMBL9681824

O=c1cc[nH]c(CNCCNCc2[nH]ccc(=O)c2O)c1O

nearest known ligand 0.33

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
CA12 O43570 1/20 0.33
CA2 P00918 1/20 0.33
CCR8 P51685 1/20 0.32
KMT2A Q03164 1/20 0.31
TYMP P19971 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL9682892 0.98 KMT2A (0.34) CA12CA2CCR8KMT2A
SCHEMBL9702106 0.98 CA12 (0.32) CA12CA2CCR8KMT2A
SCHEMBL8663414 0.76 CCR8 (0.37) CCR8KMT2A
SCHEMBL6955683 0.75 GABRA1 (0.37) CCR8KMT2A
SCHEMBL3377422 0.70 GABRA1 (0.35) CCR8KMT2A
SCHEMBL31023340 0.68 CCR8 (0.44) CCR8KMT2A
SCHEMBL594090 0.66
SCHEMBL145999 0.63
SCHEMBL13759837 0.63
SCHEMBL9744780 0.63 BLM (0.38) CCR8KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1992013841-A1 COMPLEXING AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-08-20 WO claimed
EP-0498380-A1 Complexing agents BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-08-12 EP claimed
WO-1992013841-A1 COMPLEXING AGENTS BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-08-20 WO disclosed
EP-0498380-A1 Complexing agents BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) 1992-08-12 EP disclosed