Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GABRA1 | P14867 | 1/20 | 0.37 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.37 |
| ▸ | CCR8 | P51685 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | DBH | P09172 | 2/20 | 0.32 |
| ▸ | POLB | P06746 | 2/20 | 0.32 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.32 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.32 |
| ▸ | KDM6A | O15550 | 1/20 | 0.31 |
| ▸ | KDM4A | O75164 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | KDM5C | P41229 | 1/20 | 0.31 |
| ▸ | KDM2B | Q8NHM5 | 1/20 | 0.31 |
| ▸ | DOHH | Q9BU89 | 1/20 | 0.31 |
| ▸ | KDM2A | Q9Y2K7 | 1/20 | 0.31 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.31 |
| ▸ | DAO | P14920 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8663414 | 0.81 | CCR8 (0.37) | CCR8KMT2AKDM4ELMNADBH | |
| SCHEMBL15782806 | 0.75 | HSD17B10 (0.42) | CCR8KMT2APDE3BPDE3A | |
| SCHEMBL3377422 | 0.75 | GABRA1 (0.35) | GABRA1GABRB2CCR8KMT2AKDM4E | |
| SCHEMBL9681824 | 0.75 | CA12 (0.33) | CCR8KMT2A | |
| SCHEMBL9702106 | 0.73 | CA12 (0.32) | CCR8KMT2A | |
| Hydrochloric Acid SCHEMBL9682892 | 0.73 | KMT2A (0.34) | CCR8KMT2A | |
| SCHEMBL11275335 | 0.73 | — | — | |
| SCHEMBL31023340 | 0.72 | CCR8 (0.44) | CCR8KMT2AKDM4ELMNADBH | |
| SCHEMBL20068088 | 0.72 | CCR8 (0.33) | CCR8KMT2APOLBADORA2AADORA1 | |
| SCHEMBL145999 | 0.71 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-112868657-A | Application of ethyl maltol as fungal inhibitor | 湖南农业大学 | 2021-06-01 | — | — | CN | disclosed |
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FLORIDA TURBINE TECHNOLOGIES, INC. | 2015-10-01 | — | — | US | disclosed |
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FLORIDA TURBINE TECHNOLOGIES, INC. | 2015-10-01 | — | — | US | disclosed |
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FLORIDA TURBINE TECHNOLOGIES, INC. | 2015-10-01 | — | — | US | disclosed |
| EP-1021457-B1 | METHOD FOR THE SITE SPECIFIC SYNTHESIS OF NOVEL 3-HYDROXYPYRIDIN-4(1H)-ONES DERIVATIVES FROM AMINOITOLS, PRODUCTS OBTAINED BY THIS METHOD AND THEIR APPLICATIONS | ISTITUTO BIOCHIMICO PAVESE PHA (IT) | 2003-04-09 | — | — | EP | disclosed |
| US-6177409-B1 | 2-(ALKYL OR HALOALKYL)-3-HYDROXY PYRAN-4-ONE IS HYDROXYL-PROTECTED, AND REACTED WITH AN AMINO ITOL TO SUBSTITUTED THE INTRACYCLIC OXYGEN OF PYRANONE WITH THE AMINE OF THE AMINO ITOL; IRON(III) CHELATORS FOR BLOOD DISORDERS | INSTITUTO BIOCHIMICO PAVESE PHARMA S.P.A. (IT) | 2001-01-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150274665-A1 | FLUORINATED DERIVATIVES OF 3-HYDROXYPYRIDIN-4-ONES | FH, FECH, TFRC | GABRA1 4848/4885GABRB2 4839/4885CCR8 3915/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.