Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 4/20 | 0.41 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.41 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.41 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.41 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.41 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.41 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.41 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.41 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.41 |
| ▸ | DRD1 | P21728 | 1/20 | 0.41 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.41 |
| ▸ | HTR2A | P28223 | 1/20 | 0.41 |
| ▸ | HTR2C | P28335 | 1/20 | 0.41 |
| ▸ | HRH1 | P35367 | 1/20 | 0.41 |
| ▸ | DRD3 | P35462 | 1/20 | 0.41 |
| ▸ | HTR2B | P41595 | 1/20 | 0.41 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9450752 | 0.90 | SLC6A2 (0.40) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL6966240 | 0.83 | HSP90AA1 (0.36) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL6969377 | 0.81 | OPRM1 (0.37) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL1769006 | 0.78 | SLC6A3 (0.46) | OPRM1CHRM2CHRM4CHRM5ADRA2A | |
| SCHEMBL10808078 | 0.78 | OPRM1 (0.44) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL9596460 | 0.78 | SLC6A2 (0.47) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL6968194 | 0.77 | SCN9A (0.41) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL2911607 | 0.76 | OPRM1 (0.48) | OPRM1OPRL1OPRD1OPRK1CHRM2 | |
| SCHEMBL10804626 | 0.75 | OPRM1 (0.52) | OPRM1OPRL1OPRD1OPRK1CYP2D6 | |
| SCHEMBL1925083 | 0.75 | OPRM1 (0.52) | OPRM1OPRL1OPRD1OPRK1SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |