Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAPGEF4 | Q8WZA2 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | NR2F2 | P24468 | 1/20 | 0.46 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 5/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | BCHE | P06276 | 1/20 | 0.38 |
| ▸ | CES1 | P23141 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL288931 | 0.84 | NPC1 (0.45) | NPC1NR2F2NOD2L3MBTL1POLB | |
| SCHEMBL25257871 | 0.84 | L3MBTL1 (0.45) | RAPGEF4NPC1NR2F2NOD2L3MBTL1 | |
| SCHEMBL14902121 | 0.82 | NPC1 (0.44) | RAPGEF4NPC1NR2F2NOD2L3MBTL1 | |
| SCHEMBL120851 | 0.76 | ALDH1A1 (0.42) | NPC1NR2F2NOD2L3MBTL1POLB | |
| SCHEMBL20182618 | 0.74 | POLB (0.53) | RAPGEF4NPC1NR2F2NOD2L3MBTL1 | |
| SCHEMBL9348045 | 0.74 | L3MBTL1 (0.53) | RAPGEF4NPC1NR2F2NOD2L3MBTL1 | |
| SCHEMBL17203385 | 0.73 | L3MBTL1 (0.51) | RAPGEF4NPC1NR2F2NOD2L3MBTL1 | |
| SCHEMBL2846267 | 0.73 | TSHR (0.43) | NPC1NR2F2NOD2L3MBTL1POLB | |
| SCHEMBL2845089 | 0.73 | POLB (0.43) | NPC1NR2F2NOD2L3MBTL1POLB | |
| SCHEMBL69647 | 0.71 | ALDH1A1 (0.48) | RAPGEF4KMT2AHSD17B10SMN1; SMN2CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5093467-A | Increased molecular weight | TOSOH CORPORATION (JP) | 1992-03-03 | — | — | US | disclosed |
| EP-0348189-A2 | Production of poly (arylene sulfide sulfone) | Tosoh Corporation (JP) | 1989-12-27 | — | — | EP | disclosed |