SCHEMBL9682220

SCHEMBL9682220

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nearest known ligand 0.45

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
PDE4A P27815 1/20 0.35
TDP1 Q9NUW8 1/20 0.34
USP2 O75604 1/20 0.33
SLCO1B1 Q9Y6L6 1/20 0.33
KDM4E B2RXH2 2/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682216 1.00 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL873892 0.87 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL5829662 0.87 LMNA (0.38) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL3418340 0.85 LMNA (0.37) LMNAL3MBTL1PDE4ATDP1USP2
Alcohol SCHEMBL15066415 0.84 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4274437 0.84 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4271266 0.84 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL2722434 0.84 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL4268324 0.84 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2
SCHEMBL111395 0.84 LMNA (0.35) LMNAL3MBTL1PDE4ATDP1USP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-101437488-B Oral care compositions with silicone composites COLGATE-PALMOLIVE CO. (US) 2015-11-25 CN disclosed
CN-101534802-A Disinfecting surfaces SEARETE LLC (US) 2009-09-16 CN disclosed
CN-101437488-A Oral care compositions with silicone composites COLGATE PALMOLIVE CO (US) 2009-05-20 CN disclosed
US-RE33997-E A mixture of collagen and a polymer for shaping to form contact lenses ALLERGAN, INC. (US) 1992-07-14 US disclosed