SCHEMBL9682429

SCHEMBL9682429

O=C(Oc1ccc(C(=O)OC(=O)c2ccc(OC(=O)c3ccccc3Cl)cc2C(=O)O)c(C(=O)O)c1)c1ccccc1Cl

nearest known ligand 0.56

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 9/20 0.56
MEN1 O00255 5/20 0.56
PKM P14618 2/20 0.56
ESR1 P03372 2/20 0.56
ESR2 Q92731 2/20 0.56
ALDH1A1 P00352 2/20 0.50
PDGFRB P09619 1/20 0.48
PDGFRA P16234 1/20 0.48
POLB P06746 5/20 0.48
SMN1; SMN2 Q16637 4/20 0.48
MAPT P10636 4/20 0.47
CYP1A2 P05177 2/20 0.47
CYP2C9 P11712 1/20 0.47
HPGD P15428 4/20 0.46
NPC1 O15118 3/20 0.46
RAB9A P51151 3/20 0.46
CASP3 P42574 2/20 0.46
MAPK1 P28482 1/20 0.46
SENP8 Q96LD8 1/20 0.46
SENP7 Q9BQF6 1/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11774032 0.93 KMT2A (0.59) KMT2AMEN1PKMESR1ESR2
SCHEMBL9682456 0.86 SMN1; SMN2 (0.56) KMT2AESR1ESR2ALDH1A1SMN1; SMN2
SCHEMBL9681115 0.86 MAPT (0.45) KMT2AMEN1PKMESR1ESR2
SCHEMBL11284057 0.85 ALDH1A1 (0.58) KMT2AMEN1PKMESR1ESR2
SCHEMBL29204714 0.85 ALDH1A1 (0.58) KMT2AMEN1PKMESR1ESR2
SCHEMBL9682440 0.84 ALDH1A1 (0.54) KMT2AMEN1PKMESR1ESR2
SCHEMBL11773940 0.81 TSHR (0.57) KMT2AMEN1PKMESR1ESR2
SCHEMBL24804992 0.79 KMT2A (0.67) KMT2AMEN1PKMESR1ESR2
SCHEMBL9681845 0.79 MAPT (0.49) KMT2AMEN1ALDH1A1POLBMAPT
SCHEMBL9680731 0.78 ALDH1A1 (0.44) KMT2AMEN1PKMESR1ESR2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5153335-A Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst OCCIDENTAL CHEMICAL CORPORATION (US) 1992-10-06 US claimed
EP-0460687-A2 Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides OCCIDENTAL CHEMICAL CORPORATION (US) 1991-12-11 EP claimed