Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | KMO | O15229 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.36 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681098 | 0.86 | KMT2A (0.49) | MAPTTSHRALDH1A1POLBHTT | |
| SCHEMBL9680731 | 0.83 | ALDH1A1 (0.44) | MAPTTSHRALDH1A1POLBHTT | |
| SCHEMBL9681063 | 0.82 | KDM4E (0.51) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL3435166 | 0.82 | MAPT (0.62) | MAPTTSHRSRD5A2KMOHTT | |
| SCHEMBL9682440 | 0.81 | ALDH1A1 (0.54) | MAPTTSHRALDH1A1POLBKMT2A | |
| SCHEMBL2048011 | 0.80 | ALDH1A1 (0.58) | MAPTALDH1A1POLBKMT2AMEN1 | |
| SCHEMBL9682429 | 0.79 | KMT2A (0.56) | MAPTALDH1A1POLBHTTKMT2A | |
| SCHEMBL9681115 | 0.79 | MAPT (0.45) | MAPTTSHRALDH1A1POLBKMT2A | |
| SCHEMBL9682456 | 0.79 | SMN1; SMN2 (0.56) | MAPTTSHRSRD5A2ALDH1A1KMT2A | |
| SCHEMBL9680701 | 0.77 | KMT2A (0.48) | MAPTTSHRALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |