Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 5/20 | 0.56 |
| ▸ | TSHR | P16473 | 1/20 | 0.56 |
| ▸ | CASP1 | P29466 | 1/20 | 0.56 |
| ▸ | NR1H4 | Q96RI1 | 2/20 | 0.55 |
| ▸ | RAB9A | P51151 | 7/20 | 0.54 |
| ▸ | MAPT | P10636 | 6/20 | 0.54 |
| ▸ | HPGD | P15428 | 5/20 | 0.54 |
| ▸ | NPC1 | O15118 | 5/20 | 0.54 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.45 |
| ▸ | ESR1 | P03372 | 1/20 | 0.45 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 2/20 | 0.45 |
| ▸ | SENP7 | Q9BQF6 | 2/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682440 | 0.90 | ALDH1A1 (0.54) | SMN1; SMN2TSHRCASP1NR1H4RAB9A | |
| SCHEMBL9682429 | 0.86 | KMT2A (0.56) | SMN1; SMN2RAB9AMAPTHPGDNPC1 | |
| SCHEMBL9681098 | 0.84 | KMT2A (0.49) | SMN1; SMN2TSHRCASP1MAPTKMT2A | |
| SCHEMBL9680731 | 0.81 | ALDH1A1 (0.44) | SMN1; SMN2TSHRCASP1MAPTKMT2A | |
| SCHEMBL9001094 | 0.81 | ALDH1A1 (0.59) | SMN1; SMN2TSHRCASP1KMT2AGAA | |
| SCHEMBL1501319 | 0.81 | SMN1; SMN2 (0.63) | SMN1; SMN2TSHRCASP1NR1H4RAB9A | |
| SCHEMBL9681063 | 0.81 | KDM4E (0.51) | SMN1; SMN2RAB9AMAPTHPGDNPC1 | |
| SCHEMBL9681115 | 0.80 | MAPT (0.45) | SMN1; SMN2TSHRCASP1NR1H4RAB9A | |
| SCHEMBL9681845 | 0.79 | MAPT (0.49) | TSHRMAPTKMT2AALDH1A1SRD5A2 | |
| SCHEMBL8755893 | 0.79 | MAPT (0.76) | SMN1; SMN2TSHRCASP1NR1H4RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5153335-A | Reacting halophthalic anhydride and alkali metal salt with acid or acid derivative catalyst | OCCIDENTAL CHEMICAL CORPORATION (US) | 1992-10-06 | — | — | US | claimed |
| EP-0460687-A2 | Process for the preparation of oxydiphthalic anhydride and acyloxyphthalic anhydrides | OCCIDENTAL CHEMICAL CORPORATION (US) | 1991-12-11 | — | — | EP | claimed |