Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.42 |
| ▸ | GABRP | O00591 | 1/20 | 0.39 |
| ▸ | GABRD | O14764 | 1/20 | 0.39 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.39 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.39 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.39 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.39 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.39 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.39 |
| ▸ | GABRE | P78334 | 1/20 | 0.39 |
| ▸ | GABRA6 | Q16445 | 1/20 | 0.39 |
| ▸ | GABRG1 | Q8N1C3 | 1/20 | 0.39 |
| ▸ | GABRG3 | Q99928 | 1/20 | 0.39 |
| ▸ | GABRQ | Q9UN88 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9681929 | 0.90 | SMN1; SMN2 (0.48) | SMN1; SMN2MAPTTDP1GABRPGABRD | |
| SCHEMBL9683329 | 0.82 | ALDH1A1 (0.46) | SMN1; SMN2MAPTTDP1GABRPGABRD | |
| SCHEMBL10444826 | 0.76 | ALDH1A1 (0.48) | SMN1; SMN2MAPTTDP1CYP3A4ALDH1A1 | |
| SCHEMBL9684204 | 0.73 | TDP1 (0.42) | SMN1; SMN2MAPTTDP1CYP3A4ALDH1A1 | |
| SCHEMBL10444731 | 0.72 | CYP3A4 (0.55) | SMN1; SMN2MAPTTDP1CYP3A4ALDH1A1 | |
| SCHEMBL9340200 | 0.70 | TDP1 (0.44) | SMN1; SMN2MAPTTDP1GABRPGABRD | |
| SCHEMBL9369230 | 0.70 | GABRA2 (0.46) | SMN1; SMN2MAPTTDP1GABRA2GABRB2 | |
| SCHEMBL22366851 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTTDP1CYP3A4ALDH1A1 | |
| SCHEMBL30185175 | 0.69 | SMN1; SMN2 (0.46) | SMN1; SMN2MAPTTDP1CYP3A4ALDH1A1 | |
| SCHEMBL10444468 | 0.69 | CYP3A4 (0.45) | SMN1; SMN2MAPTTDP1CYP3A4ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5079251-A | Insecticides, pesticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1992-01-07 | — | — | US | disclosed |
| EP-0408196-A2 | Pyrazinone derivatives as insecticides | IMPERIAL CHEMICAL INDUSTRIES PLC (GB) | 1991-01-16 | — | — | EP | disclosed |