Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | MC4R | P32245 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.43 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.41 |
| ▸ | DRD4 | P21917 | 1/20 | 0.40 |
| ▸ | CHRM2 | P08172 | 3/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 3/20 | 0.40 |
| ▸ | CHRM5 | P08912 | 3/20 | 0.40 |
| ▸ | CHRM1 | P11229 | 3/20 | 0.40 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | CCR5 | P51681 | 1/20 | 0.40 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682091 | 0.84 | KMT2A (0.51) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL9682607 | 0.81 | CYP2D6 (0.57) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL48088 | 0.77 | CYP2D6 (0.61) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL2916607 | 0.77 | CYP2D6 (0.61) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL9596277 | 0.77 | CYP2D6 (0.61) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL6097455 | 0.76 | CYP2D6 (0.65) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| Ethane SCHEMBL9682617 | 0.75 | CYP2D6 (0.59) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| Maleic Acid SCHEMBL9596354 | 0.74 | CYP2D6 (0.49) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL2920725 | 0.74 | CYP2D6 (0.49) | CYP2D6KMT2AMC4RALDH1A1OPRM1 | |
| SCHEMBL9682596 | 0.74 | CYP2D6 (0.49) | CYP2D6KMT2AMC4RALDH1A1DRD4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |