SCHEMBL9682607

SCHEMBL9682607

CC(O)C1CN(C(C)c2ccccc2)C1

nearest known ligand 0.57

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 1/20 0.57
MC4R P32245 1/20 0.50
OPRM1 P35372 1/20 0.46
OPRD1 P41143 1/20 0.46
OPRK1 P41145 1/20 0.46
OPRL1 P41146 1/20 0.46
KMT2A Q03164 1/20 0.43
CCR5 P51681 1/20 0.43
ALDH1A1 P00352 2/20 0.42
ADRA2A P08913 1/20 0.38
ADRA2C P18825 1/20 0.38
LMNA P02545 1/20 0.38
HIF1A Q16665 1/20 0.38
KDM4E B2RXH2 1/20 0.38
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL48088 0.81 CYP2D6 (0.61) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL2916607 0.81 CYP2D6 (0.61) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL9596277 0.81 CYP2D6 (0.61) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL9682547 0.81 CYP2D6 (0.52) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL6097455 0.80 CYP2D6 (0.65) CYP2D6MC4ROPRM1OPRD1OPRK1
Ethane SCHEMBL9682617 0.79 CYP2D6 (0.59) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL9681977 0.77 CYP2D6 (0.52) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL2921816 0.77 CYP2D6 (0.61) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL2920210 0.77 CYP2D6 (0.61) CYP2D6MC4ROPRM1OPRD1OPRK1
SCHEMBL9683895 0.76 CYP2D6 (0.55) CYP2D6MC4ROPRM1OPRD1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130309-A Cardiovascular disorders A. H. ROBINS COMPANY, INCORPORATED (US) 1992-07-14 US disclosed