SCHEMBL9681977

SCHEMBL9681977

CC(C#N)C1CN(C(C)c2ccccc2)C1

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CYP2D6 P10635 2/20 0.52
MC4R P32245 1/20 0.46
CCR5 P51681 1/20 0.40
OPRM1 P35372 3/20 0.40
OPRK1 P41145 2/20 0.40
OPRL1 P41146 2/20 0.40
OPRD1 P41143 1/20 0.40
CHRNB4 P30926 1/20 0.38
CHRNA3 P32297 1/20 0.38
KMT2A Q03164 1/20 0.37
ALDH1A1 P00352 2/20 0.36
TRPA1 O75762 1/20 0.36
TSHR P16473 1/20 0.36
HPGD P15428 1/20 0.36
NAAA Q02083 1/20 0.35
KDM4E B2RXH2 1/20 0.35
GAA P10253 1/20 0.35
L3MBTL1 Q9Y468 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2C9 P11712 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682517 0.79 CYP2D6 (0.55) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL9682607 0.77 CYP2D6 (0.57) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL6097455 0.76 CYP2D6 (0.65) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL9682060 0.75 CYP2D6 (0.50) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL9682547 0.73 CYP2D6 (0.52) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL9681972 0.73 CYP2D6 (0.47) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL48088 0.73 CYP2D6 (0.61) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL9596277 0.73 CYP2D6 (0.61) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL2916607 0.73 CYP2D6 (0.61) CYP2D6MC4RCCR5OPRM1OPRK1
SCHEMBL2920210 0.73 CYP2D6 (0.61) CYP2D6MC4RCCR5OPRM1OPRK1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5130309-A Cardiovascular disorders A. H. ROBINS COMPANY, INCORPORATED (US) 1992-07-14 US disclosed