Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.46 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.46 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.45 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MC4R | P32245 | 1/20 | 0.40 |
| ▸ | HTR1A | P08908 | 2/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682491 | 0.91 | OPRM1 (0.44) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL9683882 | 0.87 | OPRM1 (0.48) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL9682023 | 0.84 | ALDH1A1 (0.47) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL23532884 | 0.78 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL19078534 | 0.78 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL23532886 | 0.78 | OPRM1 (0.43) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL17130331 | 0.77 | CYP2D6 (0.43) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL17114344 | 0.77 | KDM4E (0.46) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 | |
| SCHEMBL18729768 | 0.77 | CYP2D6 (0.43) | OPRM1OPRD1OPRK1OPRL1CYP2D6 | |
| SCHEMBL17114345 | 0.77 | KDM4E (0.46) | OPRM1OPRD1OPRK1OPRL1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |