Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.43 |
| ▸ | OPRK1 | P41145 | 8/20 | 0.43 |
| ▸ | OPRL1 | P41146 | 8/20 | 0.43 |
| ▸ | OPRD1 | P41143 | 7/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8534618 | 0.86 | OPRM1 (0.46) | ALDH1A1OPRM1OPRK1OPRL1OPRD1 | |
| Hydrochloric Acid SCHEMBL11268886 | 0.85 | OPRM1 (0.44) | ALDH1A1OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL9682613 | 0.84 | OPRM1 (0.46) | ALDH1A1OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL9684251 | 0.79 | ALDH1A1 (0.44) | ALDH1A1OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL11415783 | 0.78 | MEN1 (0.44) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL24359355 | 0.77 | KMT2A (0.46) | ALDH1A1OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL3451288 | 0.77 | KMT2A (0.46) | ALDH1A1OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL5780577 | 0.75 | OPRM1 (0.44) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL10808130 | 0.75 | OPRM1 (0.41) | OPRM1OPRK1OPRL1OPRD1 | |
| SCHEMBL7427741 | 0.75 | ALDH1A1 (0.41) | ALDH1A1OPRM1OPRK1OPRL1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |