Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCL6 | P41182 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.44 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.44 |
| ▸ | PDE4A | P27815 | 1/20 | 0.44 |
| ▸ | KDR | P35968 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.38 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.32 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.30 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28908003 | 0.79 | BCL6 (0.47) | BCL6SMN1; SMN2ADORA3SLC6A2PDE4A | |
| SCHEMBL135748 | 0.78 | LMNA (0.31) | LMNA | |
| SCHEMBL3988247 | 0.76 | HSP90AA1 (0.36) | HSP90AA1 | |
| SCHEMBL15942897 | 0.73 | L3MBTL1 (0.48) | BCL6SMN1; SMN2ADORA3SLC6A2PDE4A | |
| SCHEMBL4264509 | 0.71 | HTT (0.38) | HTTKDM4ELMNA | |
| SCHEMBL6987146 | 0.71 | — | — | |
| SCHEMBL11022700 | 0.70 | MAPT (0.33) | MAPT | |
| Sulfuric Acid SCHEMBL128158 | 0.69 | CA1 (0.36) | KDM4E | |
| SCHEMBL11038105 | 0.69 | SCN9A (0.46) | KDM4EKCNH2SCN5ASCN9A | |
| SCHEMBL11025980 | 0.69 | MEN1 (0.43) | RAB9AGAAMAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | claimed |
| EP-0499096-A1 | Substituted arylsulfonylaminoguanidinotriazines | BAYER AG (DE) | 1992-08-19 | — | — | EP | disclosed |