Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.67 |
| ▸ | HPGD | P15428 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.50 |
| ▸ | POLB | P06746 | 3/20 | 0.50 |
| ▸ | MEN1 | O00255 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.50 |
| ▸ | APEX1 | P27695 | 1/20 | 0.50 |
| ▸ | RECQL | P46063 | 1/20 | 0.50 |
| ▸ | PKM | P14618 | 3/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.46 |
| ▸ | TP53 | P04637 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | EGFR | P00533 | 1/20 | 0.41 |
| ▸ | SRC | P12931 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700563 | 0.81 | ALDH1A1 (1.00) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL474056 | 0.77 | ALDH1A1 (0.73) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL5171751 | 0.77 | ALDH1A1 (0.68) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL14565048 | 0.77 | ALDH1A1 (0.77) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL9683762 | 0.76 | ALDH1A1 (0.76) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL2818547 | 0.76 | ALDH1A1 (0.67) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL14565012 | 0.76 | ALDH1A1 (0.75) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL29615085 | 0.75 | HPGD (0.66) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL9683737 | 0.75 | ALDH1A1 (0.70) | ALDH1A1HPGDKMT2APOLBMEN1 | |
| SCHEMBL9470369 | 0.75 | ALDH1A1 (0.49) | ALDH1A1HPGDKMT2APOLBMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |