Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.70 |
| ▸ | HPGD | P15428 | 1/20 | 0.70 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 3/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 5/20 | 0.42 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GLA | P06280 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.39 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8700563 | 0.82 | ALDH1A1 (1.00) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| SCHEMBL14565048 | 0.79 | ALDH1A1 (0.77) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| SCHEMBL14565012 | 0.77 | ALDH1A1 (0.75) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| Hydrochloric Acid SCHEMBL9683732 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| SCHEMBL474056 | 0.76 | ALDH1A1 (0.73) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| SCHEMBL5171751 | 0.76 | ALDH1A1 (0.68) | ALDH1A1HPGDPOLBTP53TDP1 | |
| SCHEMBL14565009 | 0.75 | ALDH1A1 (0.71) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| SCHEMBL9682902 | 0.75 | ALDH1A1 (0.67) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| SCHEMBL9683762 | 0.75 | ALDH1A1 (0.76) | ALDH1A1HPGDSIGMAR1POLBTP53 | |
| SCHEMBL9684601 | 0.75 | ALDH1A1 (0.62) | ALDH1A1HPGDSIGMAR1POLBTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5147883-A | Antiischemic, stroke | ADIR ET COMPAGNIE (FR) | 1992-09-15 | — | — | US | disclosed |