Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.47 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.47 |
| ▸ | NPC1 | O15118 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.44 |
| ▸ | MAPT | P10636 | 5/20 | 0.44 |
| ▸ | MEN1 | O00255 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.44 |
| ▸ | ESR1 | P03372 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | PGR | P06401 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.43 |
| ▸ | PDE4A | P27815 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682972 | 0.81 | KMT2A (0.44) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL13039041 | 0.80 | HSD17B1 (0.51) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL8335747 | 0.79 | HSD17B10 (0.57) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL8336509 | 0.79 | LMNA (0.53) | HCRTR1HCRTR2NPC1KMT2AMAPT | |
| SCHEMBL17653993 | 0.79 | HPGD (0.64) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL11111888 | 0.78 | PARP10 (0.56) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL13039039 | 0.77 | KMT2A (0.54) | NPC1SMN1; SMN2KMT2AMAPTMEN1 | |
| SCHEMBL14524363 | 0.77 | SRD5A2 (0.51) | HCRTR1HCRTR2CYP2C8 | |
| SCHEMBL13256653 | 0.77 | SRD5A2 (0.51) | HCRTR1HCRTR2CYP2C8 | |
| SCHEMBL19726963 | 0.77 | PRSS1 (0.56) | NPC1SMN1; SMN2KMT2AMAPTMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1999007694-A1 | COMPOUNDS AND USES THEREOF | ELI LILLY AND COMPANY (US) | 1999-02-18 | — | — | WO | disclosed |