Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.67 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.67 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.67 |
| ▸ | MEN1 | O00255 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.55 |
| ▸ | TP53 | P04637 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | HPGD | P15428 | 1/20 | 0.50 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.47 |
| ▸ | BRAF | P15056 | 1/20 | 0.46 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.46 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.46 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.46 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.46 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.46 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11589056 | 1.00 | ALDH1A1 (0.67) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL809256 | 0.94 | ALDH1A1 (0.76) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL11590997 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL11589601 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL5527318 | 0.89 | PTGS2 (0.50) | ALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL5028733 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL5518610 | 0.89 | PTGS2 (0.50) | ALDH1A1CYP3A4MAPK1PTGS2 | |
| SCHEMBL1024710 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL5524377 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A | |
| SCHEMBL10395087 | 0.89 | ALDH1A1 (0.84) | ALDH1A1CYP3A4MAPK1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0495222-A1 | Process for the preparaton of biphenyl derivatives by conversion of biphenyl with acid halides | BASF Aktiengesellschaft (DE) | 1992-07-22 | — | — | EP | disclosed |