SCHEMBL809256

SCHEMBL809256

O=S(=O)(c1ccc(F)cc1)c1ccc(Cl)cc1

nearest known ligand 0.76

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.76
CYP3A4 P08684 1/20 0.76
MAPK1 P28482 1/20 0.76
MEN1 O00255 2/20 0.61
KMT2A Q03164 2/20 0.61
KDM4E B2RXH2 1/20 0.55
HPGD P15428 1/20 0.55
ALOX15 P16050 1/20 0.55
HSD17B10 Q99714 1/20 0.55
PSEN1 P49768 3/20 0.50
PSEN2 P49810 3/20 0.50
APH1B Q8WW43 3/20 0.50
NCSTN Q92542 3/20 0.50
APH1A Q96BI3 3/20 0.50
PSENEN Q9NZ42 3/20 0.50
CA12 O43570 1/20 0.50
CA1 P00915 1/20 0.50
CA2 P00918 1/20 0.50
CA3 P07451 1/20 0.50
CA4 P22748 1/20 0.50

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11589056 0.94 ALDH1A1 (0.67) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL9683064 0.94 ALDH1A1 (0.67) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL4328574 0.87 HSD11B1 (0.55) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL22742 0.87 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2121770 0.87 HSD11B1 (0.55) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL30072318 0.87 HSD11B1 (0.55) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL4328031 0.87 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL79787 0.87 HSD11B1 (0.55) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL2122579 0.87 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A
SCHEMBL9313173 0.87 ALDH1A1 (1.00) ALDH1A1CYP3A4MAPK1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 120 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20170022322-A1 New polymeric materials SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-01-26 US claimed
EP-3097136-A1 NEW POLYMERIC MATERIALS Solvay Specialty Polymers USA, L.L.C. (US) 2016-11-30 EP claimed
WO-2015110477-A1 NEW POLYMERIC MATERIALS SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2015-07-30 WO claimed
US-10774183-B2 Polyarylene ether sulfones SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2020-09-15 US disclosed
EP-2917266-B1 POLYARYLENE ETHER SULFONES SOLVAY SPECIALTY POLYMERS USA (US) 2020-08-19 EP disclosed
US-20190233591-A1 POLYARYLENE ETHER SULFONES SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2019-08-01 US disclosed
US-10301432-B2 Polyarylene ether sulfones SOLVAY SPECIALTY POLYMERS USA, LLC. (US) 2019-05-28 US disclosed
US-20180282483-A1 Polyarylene ether sulfone (PAES) Polymers and Methods for Making the Same SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-10-04 US disclosed
US-9868825-B2 Polyarylene ether sulfone (PAES) polymers SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2018-01-16 US disclosed
EP-3215487-A1 POLYARYLENE ETHER SULFONE (PAES) POLYMERS AND METHODS FOR MAKING THE SAME Solvay Specialty Polymers USA, LLC. (US) 2017-09-13 EP disclosed
US-9611361-B2 Polyarylene ether sulfone (PAES) compositions SOLVAY SPECIALTY POLYMERS USA, LLC (US) 2017-04-04 US disclosed
US-5153306-A AROMATIC POLYETHERS, FLUORESCENT RESIN COMPOSITIONS CONTAINING SAME, AND PROCESSES FOR PREPARING SAME IDEMITSU KOSAN COMPANY LIMITED (JP) 1992-10-06 US disclosed
US-5086157-A Gas permeable films BAYER AKTIENGESELLSCHAFT (DE) 1992-02-04 US disclosed
US-5051495-A Reaction of dialcohol, dithiols with aromatic halogen compounds IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1991-09-24 US disclosed
EP-0336420-A2 Aromatic polyethers, fluorescent resin compositions containing same, and processes for preparing same IDEMITSU KOSAN COMPANY LIMITED (JP) 1989-10-11 EP disclosed
EP-0292211-A2 Production and/or handling of polymers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1988-11-23 EP disclosed
US-4331798-A Production of aromatic polyethers with infusible particulate substance IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1982-05-25 US disclosed
EP-0010868-A2 Production of aromatic polyethers IMPERIAL CHEMICAL INDUSTRIES PLC (GB) 1980-05-14 EP disclosed
US-4176222-A BY HEATING A BISPHENOL, DIHALOBENZENOID COMPOUND WITH SODIUM CARBONATE OR BICARBONATE AND A SECOND ALKALI METAL CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-11-27 US disclosed
US-4169178-A A BISPHENOL OR -DIPHENYL ETHER, SULFIDE, SULFONE, OR KETONE AND A DIHALOBENZENOID COMPOUND AND/OR AN O- OR P-SULFONE- OR KETO-ACTIVATED HALOPHENOL WITH AN ALKALI METAL CARBONATE IMPERIAL CHEMICAL INDUSTRIES LIMITED (GB) 1979-09-25 US disclosed