Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALPG | P10696 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | MC5R | P33032 | 4/20 | 0.45 |
| ▸ | MC4R | P32245 | 3/20 | 0.45 |
| ▸ | MC3R | P41968 | 2/20 | 0.43 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | INSR | P06213 | 1/20 | 0.41 |
| ▸ | IGF1R | P08069 | 1/20 | 0.41 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.41 |
| ▸ | MC1R | Q01726 | 1/20 | 0.41 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.41 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.40 |
| ▸ | APP | P05067 | 2/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11274390 | 0.83 | PKM (0.52) | MAPTLMNAMRGPRX4APP | |
| SCHEMBL9683129 | 0.82 | MAPT (0.47) | MAPTMEN1KMT2AHDAC8APP | |
| SCHEMBL9683512 | 0.80 | TP53 (0.46) | FFAR1MRGPRX4 | |
| SCHEMBL11569274 | 0.77 | ALDH1A1 (0.49) | MAPTMEN1KMT2A | |
| SCHEMBL9682901 | 0.77 | MAPT (0.43) | MAPTMEN1KMT2AHDAC8APP | |
| SCHEMBL9683100 | 0.77 | MAPT (0.67) | MAPTMEN1ALPGKMT2ALMNA | |
| SCHEMBL9683167 | 0.77 | HTT (0.51) | MAPTMEN1KMT2ALMNAHTT | |
| SCHEMBL27527525 | 0.76 | FFAR1 (0.60) | MEN1KMT2ACYP2A6MC5RMC4R | |
| Hydrochloric Acid SCHEMBL6419281 | 0.75 | FFAR1 (0.58) | MEN1KMT2ACYP2A6MC5RMC4R | |
| SCHEMBL6696440 | 0.75 | INSR (0.56) | MAPTMEN1ALPGKMT2AMC5R |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |