Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TBXA2R | P21731 | 15/20 | 0.56 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683033 | 0.87 | TBXA2R (0.54) | TBXA2RP2RX3 | |
| SCHEMBL9683089 | 0.87 | TBXA2R (0.73) | TBXA2R | |
| SCHEMBL9683131 | 0.86 | TBXA2R (0.76) | TBXA2R | |
| SCHEMBL9700273 | 0.85 | TBXA2R (0.77) | TBXA2RTP53 | |
| SCHEMBL9699144 | 0.82 | TBXA2R (0.76) | TBXA2R | |
| SCHEMBL9682945 | 0.81 | TBXA2R (0.62) | TBXA2R | |
| SCHEMBL9681858 | 0.79 | TBXA2R (0.77) | TBXA2R | |
| SCHEMBL9681886 | 0.79 | TBXA2R (0.68) | TBXA2R | |
| SCHEMBL9683313 | 0.79 | TBXA2R (0.64) | TBXA2RTP53 | |
| SCHEMBL9681793 | 0.79 | TBXA2R (0.67) | TBXA2RTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |