Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | SCN1A | P35498 | 1/20 | 0.35 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.35 |
| ▸ | SCN3A | Q9NY46 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | APEX1 | P27695 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7181447 | 0.88 | THRB (0.46) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL20872418 | 0.86 | TSHR (0.47) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL3280966 | 0.84 | TSHR (0.53) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL274787 | 0.83 | THRB (0.42) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL9321905 | 0.83 | THRB (0.55) | THRBTSHRALDH1A1SCN1ASCN2A | |
| Ammonia Solution, Strong SCHEMBL28737206 | 0.83 | TSHR (0.52) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL13950019 | 0.81 | THRB (0.53) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL1997757 | 0.80 | THRB (0.46) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL18593939 | 0.79 | THRB (0.49) | THRBTSHRALDH1A1SCN1ASCN2A | |
| SCHEMBL5576921 | 0.78 | THRB (0.50) | THRBTSHRALDH1A1POLBAPEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5173421-A | For high density cell culture | MITSUBISHI KASEI CORPORATION (JP) | 1992-12-22 | — | — | US | disclosed |