SCHEMBL1997757

SCHEMBL1997757

C=C(C)C(=O)OCCNCC(C)CC

nearest known ligand 0.46

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
THRB P10828 1/20 0.46
TSHR P16473 3/20 0.45
SCN1A P35498 1/20 0.36
SCN2A Q99250 1/20 0.36
SCN3A Q9NY46 1/20 0.36
ALDH1A1 P00352 2/20 0.35
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
MAPT P10636 1/20 0.30
HRH4 Q9H3N8 1/20 0.30
HRH3 Q9Y5N1 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3280966 0.85 TSHR (0.53) THRBTSHRSCN1ASCN2ASCN3A
SCHEMBL20872418 0.83 TSHR (0.47) THRBTSHRSCN1ASCN2ASCN3A
Ammonia Solution, Strong SCHEMBL28737206 0.83 TSHR (0.52) THRBTSHRSCN1ASCN2ASCN3A
SCHEMBL14565946 0.83 THRB (0.42) THRBTSHRALDH1A1POLBAPEX1
SCHEMBL7181447 0.81 THRB (0.46) THRBTSHRSCN1ASCN2ASCN3A
SCHEMBL9321905 0.80 THRB (0.55) THRBTSHRSCN1ASCN2ASCN3A
SCHEMBL9683187 0.80 THRB (0.44) THRBTSHRSCN1ASCN2ASCN3A
SCHEMBL19427342 0.79 TSHR (0.51) THRBTSHRSCN1ASCN2ASCN3A
SCHEMBL18593939 0.79 THRB (0.49) THRBTSHRSCN1ASCN2ASCN3A
SCHEMBL110870 0.79 THRB (0.55) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12036319-B2 Polyvalent sting activating compositions and uses thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-07-16 US disclosed
US-20240115741-A1 LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2024-04-11 US disclosed
CN-117402304-A Acid-activated bioorthogonal click amphiphilic polymer and nanoparticle, preparation method and application thereof 华东师范大学 2024-01-16 CN disclosed
US-11723990-B2 Library of pH responsive polymers and nanoprobes thereof THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-08-15 US disclosed
CN-116490193-A Multivalent STING activating compositions and uses thereof 德克萨斯大学系统董事会 2023-07-25 CN disclosed
EP-4210707-A1 POLYVALENT STING ACTIVATING COMPOSITIONS AND USES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2023-07-19 EP disclosed
WO-2022055929-A1 POLYVALENT STING ACTIVATING COMPOSITIONS AND USES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-03-17 WO disclosed
US-20220071903-A1 POLYVALENT STING ACTIVATING COMPOSITIONS AND USES THEREOF THE BOARD OF REGENTS OF THE UNIVERSITY OF TEXAS SYSTEM (US) 2022-03-10 US disclosed
EP-1857471-B1 POLYMERIZATION CATALYST COMPOSITION AND PROCESS FOR PRODUCTION OF POLYMER MITSUI CHEMICALS INC (JP) 2013-04-24 EP disclosed
US-7960305-B2 a mixture of a phosphazenium compound such as tetrakis[tris(dimethylamino)phosphoranylideneamino]phosphonium chloride, transition metal halides and an organic halogen compound as an activator, used for addition homo/copolymerization; living polymers MITSUI CHEMICALS, INC. (JP) 2011-06-14 US disclosed
EP-1186619-B1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof MITSUI CHEMICALS INC (JP) 2006-11-29 EP disclosed
EP-1044989-B1 Method for preparing polymer MITSUI CHEMICALS INC (JP) 2005-06-22 EP disclosed
US-6762259-B2 ACCURATE MOLECULAR WEIGHT CONTROL; POLYMERIZATION OF POLAR UNSATURATED MONOMERS IN PRESENCE OF HYDROXYCARBONYL COMPOUND AND ORGANIC OXYSALT CATALYST MITSUI CHEMICALS, INC. (JP) 2004-07-13 US disclosed
US-20040122192-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. 2004-06-24 US disclosed
US-6528599-B1 Polar unsaturated compound; anionic polymerization MITSUI CHEMICALS, INC. (JP) 2003-03-04 US disclosed
US-20030023003-A1 Process for the production of living (co)polymers and use of the (co)polymers MITSUI CHEMICALS, INC. (JP) 2003-01-30 US disclosed
EP-1266910-A1 PROCESS FOR THE PRODUCTION OF LIVING (CO)POLYMERS AND USE OF THE (CO)POLYMERS Mitsui Chemicals, Inc. (JP) 2002-12-18 EP disclosed
US-20020156207-A1 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition containing the copolymer, and uses thereof MITSUI CHEMICALS, INC. (JP) 2002-10-24 US disclosed
EP-1186619-A2 Polar group-containing olefin copolymer, process for preparing the same, thermoplastic resin composition contaning the copolymer, and uses thereof Mitsui Chemicals, Inc. (JP) 2002-03-13 EP disclosed
EP-1044989-A1 Method for preparing polymer Mitsui Chemicals, Inc. (JP) 2000-10-18 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240115741-A1 LIBRARY OF PH RESPONSIVE POLYMERS AND NANOPROBES THEREOF MSN, CD44, CD47 THRB 4596/4885TSHR 4300/4885SCN1A 4697/4885
US-12036319-B2 Polyvalent sting activating compositions and uses thereof STING1, CGAS, TLR7 THRB 4148/4885TSHR 4417/4885SCN1A 3285/4885
US-20220071903-A1 POLYVALENT STING ACTIVATING COMPOSITIONS AND USES THEREOF STING1, CGAS, TLR7 THRB 4148/4885TSHR 4417/4885SCN1A 3285/4885
US-11723990-B2 Library of pH responsive polymers and nanoprobes thereof MSN, CD44, CD47 THRB 4596/4885TSHR 4300/4885SCN1A 4697/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.