Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.74 |
| ▸ | DRD2 | P14416 | 11/20 | 0.66 |
| ▸ | TBXA2R | P21731 | 10/20 | 0.66 |
| ▸ | PTGDR2 | Q9Y5Y4 | 4/20 | 0.64 |
| ▸ | CTSG | P08311 | 2/20 | 0.63 |
| ▸ | CMA1 | P23946 | 2/20 | 0.63 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.60 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.60 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.60 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.60 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.60 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.60 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.60 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.60 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.60 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.60 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.60 |
| ▸ | MEN1 | O00255 | 1/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683001 | 0.86 | CTSG (0.66) | L3MBTL1DRD2TBXA2RPTGDR2CTSG | |
| SCHEMBL17068754 | 0.86 | L3MBTL1 (1.00) | L3MBTL1DRD2TBXA2RPTGDR2HDAC3 | |
| SCHEMBL9681428 | 0.85 | PTGDR2 (0.71) | L3MBTL1DRD2TBXA2RPTGDR2HDAC3 | |
| SCHEMBL9683250 | 0.85 | TBXA2R (0.66) | L3MBTL1DRD2TBXA2RPTGDR2CTSG | |
| SCHEMBL9681251 | 0.84 | L3MBTL1 (0.53) | L3MBTL1DRD2TBXA2RPTGDR2CTSG | |
| SCHEMBL9699251 | 0.84 | HPGD (0.54) | L3MBTL1TBXA2RMEN1KMT2A | |
| SCHEMBL9682889 | 0.82 | TBXA2R (0.64) | L3MBTL1DRD2TBXA2RCTSGCMA1 | |
| SCHEMBL5621500 | 0.81 | CTSG (0.66) | L3MBTL1DRD2TBXA2RPTGDR2CTSG | |
| SCHEMBL4307028 | 0.80 | SLC12A2 (0.67) | L3MBTL1PTGDR2CTSGCMA1KMT2A | |
| SCHEMBL7027475 | 0.79 | SLC12A2 (0.66) | L3MBTL1PTGDR2CTSGCMA1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |
| US-5021443-A | Noval benzimidazole and azabenzimiazole derivatives which are thromboxane receptor antagonists, their methods of preparation and pharmaceutical compositions in which they are present | LABORATOIRES UPSA (FR) | 1991-06-04 | — | — | US | disclosed |