SCHEMBL9683262

SCHEMBL9683262

CN(C)C(=CC=O)c1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.43
MAPT P10636 2/20 0.43
KMT2A Q03164 4/20 0.41
RECQL P46063 1/20 0.41
MAPK1 P28482 2/20 0.40
TDP1 Q9NUW8 1/20 0.40
EGFR P00533 2/20 0.39
RAB9A P51151 3/20 0.38
NPC1 O15118 2/20 0.38
HPGD P15428 1/20 0.38
HSP90AA1 P07900 2/20 0.38
HIF1A Q16665 1/20 0.37
MEN1 O00255 1/20 0.37
PKM P14618 1/20 0.37
HTT P42858 1/20 0.37
ATM Q13315 1/20 0.37
KDM4E B2RXH2 1/20 0.37
HSP90AB1 P08238 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683260 1.00 ALDH1A1 (0.43) ALDH1A1MAPTKMT2ARECQLMAPK1
SCHEMBL28919959 1.00 ALDH1A1 (0.43) ALDH1A1MAPTKMT2ARECQLMAPK1
SCHEMBL712821 0.82 MAPT (0.41) ALDH1A1MAPTTDP1RAB9ANPC1
SCHEMBL22492769 0.82 HTT (0.46) ALDH1A1KMT2AHPGDHIF1AMEN1
SCHEMBL5242504 0.82 HTT (0.46) ALDH1A1KMT2AHPGDHIF1AMEN1
SCHEMBL27748314 0.80 ALDH1A1 (0.49) ALDH1A1MAPTKMT2ATDP1RAB9A
SCHEMBL27770173 0.80 LMNA (0.44) ALDH1A1MAPTRECQLRAB9ANPC1
SCHEMBL7020743 0.80 MAPT (0.44) ALDH1A1MAPTTDP1HPGDKDM4E
SCHEMBL28291551 0.79 ALDH1A1 (0.43) ALDH1A1MAPTKMT2ARECQLEGFR
SCHEMBL27693488 0.79 ALDH1A1 (0.43) ALDH1A1MAPTKMT2ARECQLEGFR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102746172-B Preparation method of dimethylaminocinnamaldehyde HUBEI YUANCHENG PHARMACEUTICAL 2014-07-30 CN claimed
CN-102746172-A Preparation method of dimethylaminocinnamaldehyde HUBEI YUANCHENG PHARMACEUTICAL 2012-10-24 CN claimed
CN-113227752-A Enhanced, rapid, homogeneous cell staining and assay ESSENLIX 公司 2021-08-06 CN disclosed
CN-103703417-B Photosensitive composite, original edition of lithographic printing plate, the manufacture method of polyurethane and polyurethane 富士胶片株式会社 2017-07-14 CN disclosed
CN-105358531-A Mitochondrial aldehyde dehydrogenase-2 modulators and methods of use thereof UNIV LELAND STANFORD JUNIOR 2016-02-24 CN disclosed
CN-104736524-A Novel compound for imaging Tau protein accumulated in brain NAT INST RADIOLOG 2015-06-24 CN disclosed
CN-104178132-A Fluorescent compound and application thereof in medicine UNIV SICHUAN 2014-12-03 CN disclosed
CN-103266163-B Combined detection kit for detecting and identifying candida and trichomonias AUTOBIO DIAGNOSTICS CO LTD 2014-08-13 CN disclosed
CN-102746172-B Preparation method of dimethylaminocinnamaldehyde HUBEI YUANCHENG PHARMACEUTICAL 2014-07-30 CN disclosed
CN-103703417-A Photosensitive composition, master plate for planographic printing plate, polyurethane, and method for producing polyurethane FUJIFILM CORP 2014-04-02 CN disclosed
CN-103266163-A Combined detection kit for detecting and identifying candida and trichomonias AUTOBIO DIAGNOSTICS CO LTD 2013-08-28 CN disclosed
CN-1579804-A Lithographic printing plate precursor and lithographic printing method FUJI PHOTO FILM CO LTD (JP) 2005-02-16 CN disclosed
CN-1187444-C Enzymes with deaminoformyl activity KANEGAFUCHI CHEMICAL IND (JP) 2005-02-02 CN disclosed
CN-1089086-C Luminandide medicine MILLS RANDELL L (US) 2002-08-14 CN disclosed
CN-1048524-C Process for producing D-alpha amino acid KANEGAFUCHI CHEMICAL IND (JP) 2000-01-19 CN disclosed
CN-1221793-A Enzyme with deaminizating formyl activity KANEGAFUCHI CHEMICAL IND (JP) 1999-07-07 CN disclosed
CN-1102672-A Process for producing D-alpha amino acid KANEGAFUCHI CHEMICAL IND (JP) 1995-05-17 CN disclosed
US-5169958-A Reacting, 3-amino-2-propen-1-ones with magnesium halide in solvent BASF AKTIENGESELLSCHAFT (DE) 1992-12-08 US disclosed
EP-0480242-A2 Method for the production of alpha,beta-unsaturated carbonyl compounds BASF Aktiengesellschaft (DE) 1992-04-15 EP disclosed
CN-1047075-A Luminandide medicine MILLS RANDELL L (US) 1990-11-21 CN disclosed