Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.60 |
| ▸ | LMNA | P02545 | 2/20 | 0.60 |
| ▸ | THRB | P10828 | 1/20 | 0.60 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | GAA | P10253 | 1/20 | 0.53 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.49 |
| ▸ | PIK3R2 | O00459 | 1/20 | 0.49 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.49 |
| ▸ | MAOB | P27338 | 1/20 | 0.49 |
| ▸ | TNKS | O95271 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 2/20 | 0.48 |
| ▸ | MTOR | P42345 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.47 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.45 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9684057 | 0.89 | POLB (0.53) | ALDH1A1LMNATHRBNPC1GAA | |
| SCHEMBL9684981 | 0.88 | ALDH1A1 (0.46) | ALDH1A1LMNATHRBGAAPIK3CD | |
| SCHEMBL9683334 | 0.88 | MAOB (0.51) | ALDH1A1LMNATHRBPIK3CDPIK3R2 | |
| SCHEMBL9684118 | 0.86 | POLB (0.53) | ALDH1A1LMNATHRBNPC1POLB | |
| SCHEMBL9685202 | 0.85 | POLB (0.48) | ALDH1A1LMNATHRBPIK3CDPIK3R2 | |
| SCHEMBL9685250 | 0.83 | LMNA (0.56) | ALDH1A1LMNATHRBGAACYP2C9 | |
| SCHEMBL9684210 | 0.83 | MAOB (0.48) | ALDH1A1LMNATHRBNPC1MAOB | |
| SCHEMBL21187013 | 0.79 | ALDH1A1 (0.52) | ALDH1A1THRBNPC1MAOBTNKS | |
| SCHEMBL9683370 | 0.79 | KMT2A (0.50) | ALDH1A1GAAMAOBTNKSPOLB | |
| SCHEMBL9683376 | 0.79 | KMT2A (0.50) | ALDH1A1GAAMAOBTNKSPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5171865-A | Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1992-12-15 | — | — | US | disclosed |
| EP-0331078-A2 | Process for the preparation of optically active 4-oxo-1-benzopyran-2-carboxylic acid derivatives and intermediates thereof | SANWA KAGAKU KENKYUSHO CO., LTD. (JP) | 1989-09-06 | — | — | EP | disclosed |