Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 1/20 | 0.52 |
| ▸ | RAB9A | P51151 | 1/20 | 0.52 |
| ▸ | MAOB | P27338 | 5/20 | 0.50 |
| ▸ | GABRP | O00591 | 3/20 | 0.50 |
| ▸ | GABRD | O14764 | 3/20 | 0.50 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.50 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.50 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.50 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.50 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.50 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.50 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.50 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.50 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.50 |
| ▸ | GABRE | P78334 | 3/20 | 0.50 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.50 |
| ▸ | GABRG1 | Q8N1C3 | 3/20 | 0.50 |
| ▸ | GABRG3 | Q99928 | 3/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685165 | 0.82 | KDM4E (0.58) | ALDH1A1KDM4ENPC1RAB9AMAOB | |
| SCHEMBL2318176 | 0.81 | ALDH1A1 (0.67) | ALDH1A1KDM4EMAOBGABRPGABRD | |
| SCHEMBL9752059 | 0.81 | GABRP (0.55) | ALDH1A1KDM4EMAOBGABRPGABRD | |
| SCHEMBL5206777 | 0.80 | GABRP (0.54) | ALDH1A1KDM4EMAOBGABRPGABRD | |
| Hydrochloric Acid SCHEMBL8858723 | 0.80 | ALDH1A1 (0.65) | ALDH1A1KDM4EMAOBGABRPGABRD | |
| Hydrochloric Acid SCHEMBL30224994 | 0.80 | GABRP (0.54) | ALDH1A1KDM4EMAOBGABRPGABRD | |
| SCHEMBL8645195 | 0.80 | LMNA (0.67) | ALDH1A1KDM4ENPC1RAB9AMAOB | |
| SCHEMBL21174998 | 0.79 | POLB (0.51) | POLBTHRBKCNH2MCHR2MCHR1 | |
| SCHEMBL21174931 | 0.79 | POLB (0.51) | POLBTHRBKCNH2MCHR2MCHR1 | |
| SCHEMBL9683333 | 0.79 | ALDH1A1 (0.60) | ALDH1A1NPC1MAOBPOLBTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210101877-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2021-04-08 | — | — | US | disclosed |
| US-20190225592-A1 | ANTI-INFECTIVE AGENTS | UNIVERSITY OF DUNDEE (GB) | 2019-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210101877-A1 | ANTI-INFECTIVE AGENTS | C1R, RRS1, ARG1 | ALDH1A1 3749/4885KDM4E 2159/4885NPC1 2002/4885 |
| US-20190225592-A1 | ANTI-INFECTIVE AGENTS | C1R, ARG1, MSR1 | ALDH1A1 3685/4885KDM4E 2344/4885NPC1 1924/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.