Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 3/20 | 0.53 |
| ▸ | ADRB1 | P08588 | 3/20 | 0.53 |
| ▸ | ADRB3 | P13945 | 2/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.48 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.48 |
| ▸ | CNR1 | P21554 | 1/20 | 0.48 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.48 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.48 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | GLA | P06280 | 1/20 | 0.48 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11035037 | 1.00 | ADRB2 (0.53) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| SCHEMBL9684360 | 0.84 | KMT2A (0.57) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| SCHEMBL9684112 | 0.81 | MEN1 (0.76) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| SCHEMBL9683310 | 0.81 | MEN1 (0.76) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| SCHEMBL9685457 | 0.81 | MEN1 (0.76) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| SCHEMBL9684119 | 0.81 | MEN1 (0.76) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| SCHEMBL9683304 | 0.81 | MEN1 (0.76) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| SCHEMBL9684240 | 0.81 | MEN1 (0.76) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL9684970 | 0.80 | MEN1 (0.74) | ADRB2ADRB1ADRB3CYP2D6KMT2A | |
| Hydrochloric Acid SCHEMBL9684962 | 0.80 | MEN1 (0.74) | ADRB2ADRB1ADRB3CYP2D6KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166218-A | Antilipemic agents or antiglycemic agents | HOFFMANN-LA ROCHE INC. (US) | 1992-11-24 | — | — | US | disclosed |
| US-5064863-A | Catabolic activity, obesity, diabetes | HOFFMANN-LA ROCHE INC. (US) | 1991-11-12 | — | — | US | disclosed |