Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.49 |
| ▸ | HPGD | P15428 | 3/20 | 0.49 |
| ▸ | HTT | P42858 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | ATM | Q13315 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | GSK3B | P49841 | 4/20 | 0.44 |
| ▸ | NAMPT | P43490 | 3/20 | 0.44 |
| ▸ | CDK2 | P24941 | 3/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.42 |
| ▸ | STAT3 | P40763 | 1/20 | 0.42 |
| ▸ | MMP13 | P45452 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9216807 | 0.92 | ALDH1A1 (0.52) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9221111 | 0.91 | ALDH1A1 (0.51) | ALDH1A1HPGDKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9219766 | 0.89 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9682551 | 0.88 | ALDH1A1 (0.57) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9218110 | 0.88 | ALDH1A1 (0.53) | ALDH1A1HPGDKDM4ESMN1; SMN2LMNA | |
| SCHEMBL9218499 | 0.86 | POLB (0.54) | ALDH1A1HPGDSMN1; SMN2LMNATSHR | |
| SCHEMBL9212376 | 0.85 | HPGD (0.52) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9216907 | 0.85 | ALDH1A1 (0.53) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9217935 | 0.84 | LMNA (0.42) | ALDH1A1HPGDHTTKDM4ESMN1; SMN2 | |
| SCHEMBL9218881 | 0.83 | SMN1; SMN2 (0.55) | ALDH1A1HPGDHTTSMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0512570-A1 | Urea derivatives, processes for the preparation thereof and pharmaceutical composition comprising the same | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1992-11-11 | — | — | EP | disclosed |