Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 14/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.60 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.55 |
| ▸ | POLB | P06746 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.48 |
| ▸ | PKM | P14618 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.48 |
| ▸ | IDO1 | P14902 | 1/20 | 0.47 |
| ▸ | TDO2 | P48775 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.45 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682445 | 0.91 | MAPT (0.54) | MAPTL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL9683242 | 0.80 | MAPT (0.84) | MAPTL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL10935716 | 0.79 | ALDH1A1 (0.66) | MAPTL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL9682000 | 0.77 | MAPT (0.51) | MAPTL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL2465858 | 0.77 | MAPT (0.75) | MAPTL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL8034146 | 0.77 | PPARG (0.57) | MAPTSMN1; SMN2PKMMAPK1MEN1 | |
| SCHEMBL14992159 | 0.76 | MAPT (0.53) | MAPTL3MBTL1ALDH1A1NPSR1SMN1; SMN2 | |
| SCHEMBL5149985 | 0.76 | ALDH1A1 (0.67) | MAPTL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL9682067 | 0.75 | MAPT (0.76) | MAPTL3MBTL1TDP1ALDH1A1POLB | |
| SCHEMBL9681781 | 0.75 | MAPT (0.71) | MAPTL3MBTL1TDP1ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |