Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 11/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.51 |
| ▸ | PRKCQ | Q04759 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.41 |
| ▸ | XBP1 | P17861 | 1/20 | 0.41 |
| ▸ | ARNT | P27540 | 2/20 | 0.41 |
| ▸ | EPAS1 | Q99814 | 2/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.40 |
| ▸ | BCHE | P06276 | 1/20 | 0.40 |
| ▸ | ACHE | P22303 | 1/20 | 0.40 |
| ▸ | ALDH3A1 | P30838 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9682445 | 0.88 | MAPT (0.54) | MAPTALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL9682931 | 0.83 | MAPT (0.58) | MAPTALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL30740584 | 0.82 | MAPT (0.49) | MAPTALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL10487910 | 0.78 | AKR1B1 (0.53) | MEN1KMT2AL3MBTL1LMNASMN1; SMN2 | |
| SCHEMBL9683485 | 0.77 | MAPT (0.60) | MAPTALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL9681422 | 0.77 | HDAC1 (0.40) | MAPTALDH1A1 | |
| SCHEMBL12658349 | 0.75 | MAPT (0.53) | MAPTALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL3964712 | 0.73 | ALDH1A1 (0.59) | MAPTALDH1A1MAPK1PRKCQTDP1 | |
| SCHEMBL4090213 | 0.73 | HCAR3 (0.61) | MAPTALDH1A1MAPK1TDP1MEN1 | |
| SCHEMBL23270782 | 0.73 | MAPT (0.71) | MAPTALDH1A1MAPK1PRKCQTDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128359-A | Benzimidazole and azabenzimidazole derivatives which are thromboxane receptor antagonists, their methods of preparation | LABORATOIRES UPSA (FR) | 1992-07-07 | — | — | US | disclosed |
| US-5124336-A | Cardiovascular disorders | LABORATOIRES UPSA (FR) | 1992-06-23 | — | — | US | disclosed |