Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | DRD4 | P21917 | 4/20 | 0.47 |
| ▸ | HTR1A | P08908 | 2/20 | 0.47 |
| ▸ | HTR2A | P28223 | 2/20 | 0.47 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.47 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.47 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.47 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.47 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | HTR2B | P41595 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.46 |
| ▸ | HTR1D | P28221 | 1/20 | 0.45 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | CA12 | O43570 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7397119 | 0.86 | DRD2 (0.63) | DRD2DRD4HTR1AHTR2AADRA2A | |
| SCHEMBL286554 | 0.79 | GID4 (0.38) | HTR2ADRD1HTR2BALDH1A1TAAR1 | |
| SCHEMBL9052776 | 0.78 | DRD2 (0.58) | DRD2DRD4HTR1AHTR2AADRA2A | |
| SCHEMBL20964168 | 0.77 | KEAP1 (0.57) | DRD2HTR1ADRD3ALDH1A1TAAR1 | |
| SCHEMBL14903644 | 0.77 | KEAP1 (0.57) | DRD2HTR1ADRD3ALDH1A1TAAR1 | |
| SCHEMBL7404891 | 0.77 | DRD4 (0.79) | DRD2DRD4HTR1AHTR2AADRA2A | |
| SCHEMBL297981 | 0.77 | KCNJ1 (0.41) | DRD2HTR2ADRD1HTR2BHTR1D | |
| Hydrochloric Acid SCHEMBL8184617 | 0.76 | DRD4 (0.77) | DRD2DRD4HTR1AHTR2AADRA2A | |
| Parachlorophenol SCHEMBL9031735 | 0.76 | DRD2 (0.52) | DRD2DRD4HTR1AHTR2AADRA2A | |
| SCHEMBL14903763 | 0.75 | TAAR1 (0.78) | DRD2HTR1ATAAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5128369-A | Antiallergens, bronchodilator agents | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1992-07-07 | — | — | US | disclosed |
| EP-0404197-A2 | Arylalkylamine derivatives | KYOWA HAKKO KOGYO CO., LTD. (JP) | 1990-12-27 | — | — | EP | disclosed |