Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.53 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.52 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.46 |
| ▸ | CA12 | O43570 | 1/20 | 0.46 |
| ▸ | CA1 | P00915 | 1/20 | 0.46 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | CA7 | P43166 | 1/20 | 0.46 |
| ▸ | CA9 | Q16790 | 1/20 | 0.46 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.46 |
| ▸ | MAOB | P27338 | 1/20 | 0.45 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.45 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | HSD17B1 | P14061 | 1/20 | 0.44 |
| ▸ | DHODH | Q02127 | 3/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6498971 | 0.91 | HDAC7 (0.57) | HSD17B10HDAC7CSNK2A1MCL1ALDH1A1 | |
| SCHEMBL9683494 | 0.89 | HSD17B10 (0.58) | HSD17B10HDAC7CSNK2A1MCL1ALDH1A1 | |
| SCHEMBL27606663 | 0.87 | HDAC7 (0.50) | HSD17B10HDAC7CSNK2A1MCL1CA12 | |
| SCHEMBL11154359 | 0.86 | ALDH1A1 (0.55) | HDAC7CSNK2A1MCL1ALDH1A1CA12 | |
| SCHEMBL3229733 | 0.85 | HDAC7 (0.70) | HSD17B10HDAC7CSNK2A1ALDH1A1TSHR | |
| SCHEMBL900834 | 0.85 | HSD17B10 (0.71) | HSD17B10ALDH1A1CA12CA1CA2 | |
| SCHEMBL6489883 | 0.84 | NPC1 (0.51) | HSD17B10HDAC7CSNK2A1MCL1ALDH1A1 | |
| SCHEMBL6500578 | 0.84 | HDAC7 (0.51) | HSD17B10HDAC7CSNK2A1MCL1ALDH1A1 | |
| SCHEMBL2785635 | 0.83 | HSD17B10 (0.68) | HSD17B10MCL1ALDH1A1CA12CA1 | |
| SCHEMBL8673355 | 0.82 | CSNK2A1 (0.59) | HDAC7CSNK2A1MCL1ALDH1A1CA12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5089590-A | LIQUID CRYSTALLINE COMPOUNDS, THEIR PRODUCTION AND THEIR USE AS MODIFIERS FOR POLYCARBONATES, POLYESTER CARBONATES AND POLYESTERS | BAYER AKTIENGESELLSCHAFT (DE) | 1992-02-18 | — | — | US | disclosed |
| US-5084549-A | Aromatic polyesters as thermoplastic molding materials | BAYER AKTIENGESELLSCHAFT (DE) | 1992-01-28 | — | — | US | disclosed |