Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | RAB9A | P51151 | 2/20 | 0.51 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.51 |
| ▸ | AURKA | O14965 | 1/20 | 0.50 |
| ▸ | TPX2 | Q9ULW0 | 1/20 | 0.50 |
| ▸ | ANO1 | Q5XXA6 | 1/20 | 0.48 |
| ▸ | DHODH | Q02127 | 3/20 | 0.48 |
| ▸ | METAP2 | P50579 | 1/20 | 0.48 |
| ▸ | PPARG | P37231 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.48 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.48 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.48 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.48 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.48 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.48 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.48 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.47 |
| ▸ | AKR1C1 | Q04828 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 2/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6492374 | 0.90 | DHODH (0.55) | NPC1RAB9AHDAC7AURKATPX2 | |
| SCHEMBL6498971 | 0.89 | HDAC7 (0.57) | NPC1RAB9AHDAC7PRKAB2PRKAG1 | |
| SCHEMBL6499129 | 0.86 | HSD17B10 (0.51) | NPC1RAB9AAURKATPX2ANO1 | |
| SCHEMBL809394 | 0.85 | ALDH1A1 (0.59) | NPC1RAB9AAURKATPX2ANO1 | |
| SCHEMBL11154359 | 0.84 | ALDH1A1 (0.55) | NPC1RAB9AHDAC7SMN1; SMN2ALDH1A1 | |
| SCHEMBL9683573 | 0.84 | HSD17B10 (0.58) | HDAC7DHODHPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL3229733 | 0.84 | HDAC7 (0.70) | HDAC7AKR1C2AKR1C1ALDH1A1TSHR | |
| SCHEMBL6549614 | 0.83 | PRKAB2 (0.50) | HDAC7DHODHPRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6500578 | 0.83 | HDAC7 (0.51) | NPC1RAB9AHDAC7DHODHPRKAB2 | |
| SCHEMBL5535848 | 0.82 | SLC6A3 (0.65) | NPC1RAB9AHDAC7TP53SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | DAISO CO., LTD. (JP) | 2005-02-17 | — | — | US | disclosed |
| US-20040157866-A1 | Amide compounds | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-08-12 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040157866-A1 | Amide compounds | APOB, NR1H2, NR1H3 | NPC1 40/4885RAB9A 4004/4885HDAC7 975/4885 |
| US-20050038035-A1 | Heterocyclic amide compounds as apolipoprotein b inhibitors | APOB, APOL1, CTRB2 | NPC1 100/4885RAB9A 4382/4885HDAC7 876/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.