Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683613 | 1.00 | LMNA (0.32) | LMNAESR1KCNH2MAPTTSHR | |
| SCHEMBL468693 | 0.80 | ALDH1A1 (0.40) | LMNAMAPTTSHR | |
| SCHEMBL468692 | 0.80 | ALDH1A1 (0.40) | LMNAMAPTTSHR | |
| SCHEMBL9159179 | 0.75 | LMNA (0.37) | LMNAMAPTTSHR | |
| SCHEMBL8581978 | 0.75 | LMNA (0.37) | LMNAMAPTTSHR | |
| SCHEMBL25504659 | 0.74 | LMNA (0.36) | LMNAMAPTTSHR | |
| SCHEMBL9341590 | 0.74 | ALDH1A1 (0.50) | LMNATSHR | |
| SCHEMBL25475988 | 0.73 | LMNA (0.39) | LMNAMAPTTSHR | |
| SCHEMBL5350166 | 0.73 | SLC22A6 (0.33) | MAPT | |
| SCHEMBL7834369 | 0.73 | SLC22A6 (0.33) | MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5144073-A | Decyclization of diketopiperazine intermediates | EASTMAN CHEMICAL COMPANY | 1992-09-01 | — | — | US | disclosed |