Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | CA1 | P00915 | 2/20 | 0.47 |
| ▸ | CA2 | P00918 | 2/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | KCNJ1 | P48048 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | BCL9 | O00512 | 1/20 | 0.43 |
| ▸ | CTNNB1 | P35222 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4348693 | 0.89 | HRH3 (0.50) | ACHEALDH1A1KMT2AHPGDKCNJ1 | |
| SCHEMBL6181435 | 0.86 | ALDH1A1 (0.49) | ACHEALDH1A1KMT2AHPGDCYP3A4 | |
| SCHEMBL28155350 | 0.84 | CA1 (0.45) | ACHECA1CA2BCHEALDH1A1 | |
| SCHEMBL17542297 | 0.79 | ALDH1A1 (0.42) | ACHECA1CA2BCHEALDH1A1 | |
| SCHEMBL9232916 | 0.77 | KCNJ1 (0.56) | ALDH1A1KCNJ1KCNH2SIGMAR1HRH3 | |
| SCHEMBL11044966 | 0.77 | EPHX2 (0.54) | ACHECA1CA2BCHEALDH1A1 | |
| SCHEMBL27573482 | 0.76 | MGLL (0.48) | ACHEBCHEALDH1A1KDM4E | |
| SCHEMBL1830606 | 0.76 | POLB (0.49) | ACHEALDH1A1KCNJ1KCNH2SIGMAR1 | |
| SCHEMBL14612865 | 0.76 | HRH3 (0.46) | HRH3 | |
| SCHEMBL16514640 | 0.75 | SIGMAR1 (0.47) | ACHEBCHEALDH1A1KCNJ1KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5130309-A | Cardiovascular disorders | A. H. ROBINS COMPANY, INCORPORATED (US) | 1992-07-14 | — | — | US | disclosed |