Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.41 |
| ▸ | ADORA2A | P29274 | 5/20 | 0.41 |
| ▸ | ADORA1 | P30542 | 4/20 | 0.41 |
| ▸ | AHCY | P23526 | 4/20 | 0.40 |
| ▸ | PI4KA | P42356 | 1/20 | 0.40 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.40 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.40 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.40 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.39 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.39 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.39 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.39 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858133 | 0.88 | FGFR1 (0.47) | FGFR1CYP3A4CYP2D6SLC22A6 | |
| SCHEMBL9685592 | 0.85 | CYP3A4 (0.47) | FGFR1CYP3A4ADORA2AADORA1AHCY | |
| SCHEMBL9858312 | 0.85 | FGFR1 (0.49) | FGFR1CYP3A4ADORA2AADORA1CYP2D6 | |
| SCHEMBL9684215 | 0.85 | ADORA2A (0.40) | FGFR1CYP3A4ADORA2AADORA1AHCY | |
| SCHEMBL9683414 | 0.83 | ABCB11 (0.36) | FGFR1CYP3A4ADORA2AADORA1PI4KA | |
| SCHEMBL9683794 | 0.82 | CYP3A4 (0.41) | FGFR1CYP3A4ADORA2AADORA1AHCY | |
| SCHEMBL9684337 | 0.81 | HSP90AA1 (0.35) | HSP90AA1HSP90AB1 | |
| SCHEMBL9555568 | 0.81 | FAP (0.44) | FGFR1CYP3A4ADORA2AADORA1AHCY | |
| SCHEMBL9555527 | 0.81 | FAP (0.44) | FGFR1CYP3A4ADORA2AADORA1AHCY | |
| SCHEMBL9417158 | 0.81 | FAP (0.44) | FGFR1CYP3A4ADORA2AADORA1AHCY |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |