Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.47 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.47 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | AHCY | P23526 | 6/20 | 0.44 |
| ▸ | ENPP1 | P22413 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9858153 | 0.86 | FGFR1 (0.60) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9683749 | 0.85 | FGFR1 (0.42) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9857605 | 0.84 | FGFR1 (0.57) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9685542 | 0.83 | CYP3A4 (0.45) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9685561 | 0.80 | CYP3A4 (0.47) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9684183 | 0.79 | HPRT1 (0.63) | CYP3A4 | |
| SCHEMBL9555564 | 0.78 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9555809 | 0.78 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9417190 | 0.78 | CYP3A4 (0.55) | CYP3A4FGFR1SLC22A6ADORA2AADORA1 | |
| SCHEMBL9858133 | 0.78 | FGFR1 (0.47) | CYP3A4FGFR1SLC22A6ENPP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | claimed |
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |
| EP-0369944-A1 | Substituted oxadiamino butanes | CIBA-GEIGY AG (CH) | 1990-05-23 | — | — | EP | disclosed |