Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | ENPEP | Q07075 | 2/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.31 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.31 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.31 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9685210 | 0.84 | — | — | |
| SCHEMBL9684383 | 0.73 | ALDH1A1 (0.34) | ALDH1A1ENPEPTDP1S1PR2S1PR1 | |
| SCHEMBL10439455 | 0.71 | — | — | |
| SCHEMBL10439454 | 0.71 | — | — | |
| SCHEMBL9685464 | 0.67 | S1PR1 (0.37) | ALDH1A1ENPEPTDP1S1PR2S1PR1 | |
| SCHEMBL7110398 | 0.64 | ANPEP (0.34) | — | |
| SCHEMBL9684363 | 0.64 | ALDH1A1 (0.35) | ALDH1A1ENPEPTDP1S1PR2S1PR1 | |
| SCHEMBL10448173 | 0.64 | FDPS (0.32) | — | |
| SCHEMBL16155275 | 0.63 | — | — | |
| SCHEMBL6599047 | 0.62 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5166198-A | Herpes virus infections | BEECHAM P.L.C. (GB) | 1992-11-24 | — | — | US | disclosed |
| EP-0404296-A1 | Phosphono derivatives of purine with antiviral activity | Beecham Group p.l.c. (GB) | 1990-12-27 | — | — | EP | disclosed |