SCHEMBL9684383

SCHEMBL9684383

CC(C)(C)[Si](C)(C)OC(CO)CCP(=O)(O)O

nearest known ligand 0.34

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.34
TDP1 Q9NUW8 1/20 0.34
GRM4 Q14833 1/20 0.32
ENPEP Q07075 1/20 0.31
S1PR2 O95136 5/20 0.30
S1PR1 P21453 5/20 0.30
S1PR3 Q99500 5/20 0.30
S1PR4 O95977 4/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9683768 0.81 PPARD (0.43)
SCHEMBL31411083 0.78
SCHEMBL5806133 0.78 PRKCA (0.32)
SCHEMBL9684363 0.73 ALDH1A1 (0.35) ALDH1A1TDP1GRM4ENPEPS1PR2
SCHEMBL9683775 0.73 ALDH1A1 (0.32) ALDH1A1TDP1GRM4ENPEPS1PR2
SCHEMBL4570492 0.72
SCHEMBL15524497 0.72
SCHEMBL15524499 0.72
SCHEMBL9684165 0.71 PPARD (0.38)
SCHEMBL18027539 0.71

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5166198-A Herpes virus infections BEECHAM P.L.C. (GB) 1992-11-24 US disclosed
EP-0404296-A1 Phosphono derivatives of purine with antiviral activity Beecham Group p.l.c. (GB) 1990-12-27 EP disclosed
EP-0374946-A2 Method for the detection of carbohydrate-containing compounds Roche Diagnostics GmbH (DE) 1990-06-27 EP disclosed