SCHEMBL9683786

SCHEMBL9683786

NC(=O)CC1C(=O)Nc2cc(S(N)(=O)=O)sc2S1(=O)=O

nearest known ligand 0.61

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
CA2 P00918 20/20 0.61
CA1 P00915 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9682131 0.90 CA2 (0.61) CA2CA1
SCHEMBL9682638 0.87 CA2 (0.58) CA2CA1
SCHEMBL7520641 0.78 CA2 (0.62) CA2CA1
SCHEMBL9683128 0.77 CA2 (0.55) CA2CA1
SCHEMBL7520645 0.77 CA2 (1.00) CA2
SCHEMBL9683134 0.73 CA2 (0.51) CA2CA1
SCHEMBL9682708 0.72 CA2 (0.81) CA2
SCHEMBL7526891 0.70 CA2 (1.00) CA2
SCHEMBL9682085 0.70 CA2 (0.61) CA2CA1
SCHEMBL9682149 0.65 CA2 (1.00) CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0479480-A2 Substituted thieno(2,3-B)(1,4)thiazine-6-sulfonamides as antiglaucoma agents MERCK & CO. INC. (US) 1992-04-08 EP disclosed
US-5093332-A SUBSTITUTED THIENO(2,3-B)(1,4)THIAZINE-6-SULFONAMIDES AS ANTIGLAUCOMA AGENTS MERCK & CO., INC. (US) 1992-03-03 US disclosed